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Interactions & Medical Disclaimers

🛡️ If You Must Vaccinate Mid-Protocol

🗓️ Timing Recommendations:

  • Space vaccination at least 2 weeks away from a known Herxheimer phase

  • Choose single-antigen vaccines (one disease per dose) when possible

💊 Support With:

  • Vitamin E + Magnesium → Nerve protection

  • Milk Thistle or Boswellia → Liver support

  • Electrolytes + Extra Water → Help flush the system

👀 Monitor For:

  • Sudden behavior changes

  • Toe dragging, fatigue, twitching

  • Appetite or coat texture shifts

💬 From Paige:

“You’re not crazy if your horse reacts weirdly to a vaccine during detox. That immune system is already working. Don’t stack too many enemies. Space them out. Support the body. Let it win one battle at a time.”

💊 EPMSD + Prescription EPM Meds

Safe Combinations, Timing Tips & What to Watch

🧠 Can EPMSD Be Used With Prescription Medications?

✅ Yes — in most cases.
EPMSD is designed to work synergistically with:

  • Toltrazuril / Baycox

  • Diclazuril / Protazil

  • Ponazuril / Marquis

  • Decoquinate + Levamisole (DEC/Lev)

  • DMSO (IV, oral, or topical)

EPMSD does not interfere with prescription drugs — but proper timing, hydration, and monitoring are key.

🧪 Medication Interactions

Medication ✅ Use with EPMSD? Notes
Toltrazuril ✅ Yes Safe to co-administer; EPMSD aids detox
Ponazuril ✅ Yes May enhance absorption once gut heals
Diclazuril ✅ Yes Compatible; space doses to avoid GI stress
DEC/Levamisole ⚠️ Caution Wait 7–10 days between protocols — don’t overlap
DMSO (any form) ✅ With Care May increase uptake of EPMSD’s botanicals — monitor closely

⚖️ Recommended Timing Strategy

💊 If Already Using a Prescription:

  • Start EPMSD 5–7 days into the drug protocol

  • Drug clears protozoa → EPMSD supports tissue repair

🕐 Dual Use:

  • Space doses 6–12 hours apart

    • AM: Prescription

    • PM: EPMSD (or vice versa)

  • Ensure free-choice water + salt

⛔ If Using DMSO:

  • Reduce EPMSD dose by 25% for the first 3 days

  • Monitor for:

    • Twitching

    • Excess sweating

    • Gut sensitivity

⚠️ Signs to Watch When Combining:

  • Loose stool, crusting, strong body odor

  • Mood swings, sleepiness

  • Temporary neurological flares

  • Appetite shifts

✅ These are Herxheimer signs — not danger. Keep hydration and detox support steady.

🧂 Recommended Add-Ons:

  • Milk Thistle → Liver support

  • Boswellia or White Willow → Natural inflammation buffer

  • Magnesium + Salt → Electrolyte + nerve support

  • Flax / Soaked Beet Pulp → Gut soothing

  • Chlorella or Clay → Optional binder (1x/day away from meds)

💬 From Paige:

“It’s not about choosing one or the other — it’s about working with your vet and nature. EPMSD bridges the chemical and botanical worlds.”

🛠️ Best Practice Recommendations

Support Type Benefit Notes
Vitamin E (2,000–5,000 IU) Hormonal + follicle support Use during detox or pre-breeding
Magnesium + Sea Salt Muscle tone, adrenal balance Especially critical for stallions
Milk Thistle / Dandelion Liver detox support Avoid high doses early in pregnancy
Flax / Chia Seeds Gut + skin + hormone balance Safe in all phases

🚫 Do Not Use EPMSD In:

  • Mares with high-risk pregnancies

  • During embryo transfer, unless cleared by vet

  • If mare is past Day 25 pregnant without reproductive specialist support

💬 From Paige:

“We’ve seen incredible results with mares who couldn’t cycle — and stallions who came alive again after detox. But with pregnancy? That’s sacred ground. Always time it right.”

💉 Injection Timing & Procedure Safety During EPMSD

🧬 Why Timing Matters

During detox, the body is in elimination mode. Introducing procedures can:

  • Overload detox organs

  • Provoke inflammation

  • Mask critical symptoms

  • Delay neurological repair

⚠️ Procedure Safety Table

Procedure Risk Level Notes
Sedation (e.g., Dormosedan) ⚠️ Moderate May suppress vagus nerve feedback
Joint Injections 🚫 High Suppresses inflammation, may worsen parasite load
Nerve Blocks ⚠️ Moderate Can confuse detox symptom tracking
Hock/Stifle/SI Injections 🚫 Not advised Blunts blood flow needed for healing
Shockwave / PEMF / Bodywork ✅ Safe Avoid during visible Herxheimer flares
IV Antibiotics / DMSO ✅ With Vet Reduce EPMSD by 25% temporarily with DMSO

📆 Timing Strategy

🕐 Pre-Procedural:

  • Avoid vet procedures during Days 1–30

  • Best window: Days 40–60

  • If using sedatives or steroids → pause EPMSD 48 hours before

💡 Why Injections May Be Less Effective Mid-Detox

  • Detox may eliminate meds faster

  • Blood flow is rerouted to healing tissues

  • Nerves may remap, making lameness hard to detect

  • Anti-inflammatories can suppress immune response if given too early

✅ Safer Alternatives During EPMSD

  • Boswellia or White Willow Bark

  • Magnesium Glycinate + Flaxseed

  • Topical Arnica or Liniments

  • Gentle bodywork, massage, or movement

🐴 Client Tip:

If a vet procedure is necessary:

  • Request single injections only

  • Space procedures 2 weeks away from any Herxheimer flare

  • Avoid joint injections unless performance-critical

  • Document before/after behavior

📩 Planning a vet visit during detox?
Email: support@oldwestholistic.shop
We’ll help you time it safely.